FibroGen is dedicated to creating innovative, first-in-class medicines for the treatment of chronic and life-threatening or debilitating conditions such as anemia in chronic kidney disease (CKD), anemia in myelodysplastic syndromes (MDS), idiopathic pulmonary fibrosis (IPF), pancreatic cancer, and Duchenne muscular dystrophy (DMD). The products we develop represent more than isolated opportunities or single indications — we see our products as representing broader platforms that enable us to continue to investigate discrete pathways and mediators that are central to multiple diseases.
- Partnered
- Wholly-Owned
- Medical Device
1 IND Approved for Phase 3 Study
2 CTA Approved for Phase 2/3 Study
Roxadustat
Roxadustat is a first-in-class, oral small molecule hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) currently being evaluated in multiple Phase 3 clinical trials globally for the treatment of anemia in patients with chronic kidney disease (CKD). Roxadustat is in Phase 3 clinical development in the U.S. and Europe and in Phase 2/3 development in China for anemia associated with myelodysplastic syndromes (MDS), and in a Phase 2 U.S. trial for treatment of chemotherapy-induced anemia (CIA).
Pamrevlumab
Pamrevlumab, our proprietary fully human antibody, represents a potential treatment for a broad array of fibrotic and proliferative disorders that affect organ systems throughout the body.
FG-5200
We are developing FG-5200, a biosynthetic cornea containing our proprietary recombinant human collagen, for the treatment of corneal blindness.