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RECOMBINANT HUMAN COLLAGENS AND GELATINS FOR RESEARCH PURPOSES

FibroGen is the first to bring recombinant human collagens and gelatins to the market. We produce fully synthetic, well-characterized, highly purified products that afford customers reproducibility and flexibility not achievable with collagen and gelatin derived from animal sources. Our technology allows us to provide customers with genetically distinct collagen types in pure form. FibroGen's proprietary recombinant methods also enable the genetic engineering of collagens and gelatins with specific traits tailored to our customers’ specifications to enhance the final end-user product, ensure batch-to-batch consistency, and reduce manufacturing steps.

Recombinant gelatin and FibroGen^® recombinant collagen can be provided in "market standard" formulations, both dry and in solution, for research purposes. Please see below for product availability.

Additionally, because FibroGen's collagen and gelatin products are gene-engineered synthetic materials, we are able to work with our customers to design "market preferred" formulations by manipulating the materials to enhance or delete particular characteristics as well as to modify the materials to achieve specific physical presentations. FibroGen is working with companies worldwide in the pharmaceutical, vaccine, medical device, diagnostic, industrial, food, cosmetic, and nutraceutical businesses. We would be delighted to open a dialogue with you about your needs. Please contact us through our Business Development Group at bd@fibrogen.com or call us at 1-800-720-7203 (in the US), or +1-415-978-1280 (international or local).

HOW TO ORDER

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Recombinant Human Collagen I

Order Number:	RhC1-003
Quantity:	1.0g, 0.5g, 0.1g
Concentration:	3.0 mg/mL ±0.3 mg/mL in 10mM HCl
Source:	DNA sequences encoding the human proalpha1(I), proalpha2(I) and both alpha and beta subunits of prolyl hydroxylase were co-expressed in the yeast Pichia pastoris. Procollagen I was converted into mature collagen by a controlled proteinase digestion.
Purity:	>95% as judged by SDS-PAGE
SDS-PAGE:	Corresponds to standard
Solubility:	Further dilution with HCl (10mM)
Storage:	2°C - 8°C.

1.0	$1575
0.5	$1050
0.1	$315

Recombinant Human Collagen III

Order Number:	RhC3-012
Quantity:	1.0g, 0.5g, 0.1g
Concentration:	3.0 mg/mL in ±0.3 mg/mL 10mM HCl<
Source:	DNA sequences encoding the human proalpha1(III) and both alpha and beta subunits of prolyl hydroxylase were co-expressed in the yeast Pichia pastoris. Procollagen III was converted into mature collagen by a controlled proteinase digestion.
Purity:	>95% as judged by SDS-PAGE
SDS-PAGE:	Corresponds to standard
Solubility:	Further dilution with HCl (10mM)
Storage:	2°C - 8°C.

1.0	$1575
0.5	$1050
0.1	$315

8.5 kd Recombinant Gelatin

Order Number:	RhG8.5-005
Quantity:	1.0g, 0.5g
Concentration:
Source:	recombinant, human
Purity:	>95% by SDS-PAGE
Solubility:	At least 20 mg/mL in H2O
Storage:	Room Temperature in lyophilized form; -20°C in liquid form

1.0	$790
0.5	$395

100 kd Recombinant Gelatin

Order Number:	RhG100-001
Quantity:	1.0g, 0.5g
Source:	recombinant, human
Purity:	>95% by SDS-PAGE
Solubility:	At least 20 mg/mL in H2O
Storage:	Room Temperature in lyophilized form; -20°C in liquid form

1.0	$790
0.5	$395

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