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Vascular Biology
One of the longer-term effects of hypoxia on the body is to promote
changes in the vasculature (blood vessels), such as the growth of
new blood vessels (neovascularization) that help to restore the
normal delivery of oxygen to the tissues. The ability to
pharmacologically control HIF-mediated effects on vascular biology
with small molecules is the goal of FibroGen's research programs
that could have therapeutic applications in medical areas such as
pulmonary dysplasia, wound healing, peripheral vascular disease,
and coronary artery disease. |
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