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Transforming Growth Factor-beta (TGF-beta) Inhibition
TGF-beta is a regulatory protein that has multiple functions, including an early role in the inflammatory response to injury and a central role in triggering the chain of events leading to the induction of CTGF and scarring. FibroGen scientists are working on small molecules that selectively inhibit TGF-beta for the potential treatment of chronic fibrosis and cancer without affecting the beneficial activities of this growth factor.


 
FibroGen 2008 (C)